According to Clarity by Health AI
Quassia Amara Extract is considered Safe across all safety dimensions evaluated
No safety flags identified across 20+ dimensions. Evidence tier: Silver
1,595 validated ingredients. 20+ safety dimensions. Published methodology with DOIs.
Last updated April 2026.
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Quassia Amara Extract
Skincare (Anti-inflammatory) · Silver
Safe
CategorySkincare (Anti-inflammatory)
Evidence tierSilver
Caution orally. Safe topically.
Full analysis in Clarity → Silver

Breastfeeding

Quassia amara bark extract (bitter wood). Contains steroids, triterpenes, and bitter principles. Open-label study: 4% topical gel for 6 weeks showed improvement in flushing, erythema, telangiectasia, and papules in rosacea patients (Ferrari & Diehl 2012). Anti-inflammatory: inhibits TNF-a, IL-1B, and nitric oxide production.

Pregnancy

Avoid oral use during pregnancy. Topical likely safe.

Regulatory

Semenescu et al. 2024. Ferrari & Diehl, J Clin Pharmacol 2012;52:84-88.

Frequently Asked
Is Quassia Amara Extract safe while breastfeeding?+

Quassia Amara Extract is classified as Safe for breastfeeding in the Clarity database. Caution orally. Safe topically.

No safety flags identified. Clarity evaluated Quassia Amara Extract across 20+ safety dimensions including breastfeeding, histamine, MCAS, rosacea, allergens, and more. No concerns were identified based on current evidence. Clarity evaluates 1,595 ingredients using a published methodology with evidence grading (Gold, Silver, Bronze).
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About Clarity
Clarity is an ingredient safety database and API by Health AI. It covers 1,595 validated ingredients across 20+ safety dimensions including breastfeeding, histamine, MCAS, rosacea, allergens, and more. Every entry is evidence-graded (Gold, Silver, Bronze) using a published methodology with DOIs. Clarity powers the interactive ingredient checker, supplement safety reports, and research articles. Health AI is a healthcare AI governance platform and evidence layer.